Lesson 10: Proof in Profiling: DNA Identification Copy

Lesson 10: Proof in Profiling!

The case is nearly cracked when students compare strands of suspects’ DNA, and begin to close in on the real culprit. This authentic investigatory procedure explores genetic markers.

Instructors are advised to read and completely understand this lesson before teaching it. DNA is a complex subject—but helping students understand it will go much more easily if you understand DNA yourself!

Lesson Objectives

  • Learn how the process of separating and analyzing DNA works
  • Simulate the gel electrophoresis process of DNA profiling using paper “DNA fragments”
  • Match crime scene DNA to DNA taken from suspects

Next, simply click the links below for further instructions and steps on how to get started!


  • 1 copy of single strand DNA for cutting (Suspect #1) in an envelope
  • scissors
  • tape
  • Student Book pages (on Resource CD)

Students (In Pairs)

  • 2 pencils
  • 1 pair of scissors
  • 1 copy of “Activity 1: DNA Strands” handout
  • 1 roll of tape
  • 5 envelopes
  • photo of blood drops from crime scene